R112 is a fast and reversible inhibitor of spleen tyrosine kinase (Syk) kinase. R112 inhibits Syk kinase activity with an IC50 value of 226 nM and a Ki value of 96 nM. R112 inhibits IgE-FcepsilonRI signaling pathway. R112 can be used for the research of allergic rhinitis[1].
Molecular Weight:
312.30
Purity:
98.90
CAS Number:
[575474-82-7]
Formula:
C16H13FN4O2
Target:
Syk
Application Notes:
MCE Product type: Reference compound
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