Rolapitant hydrochloride hydrate (SCH619734 hydrochloride hydrate) is a potent, selective, long-acting and orally active neurokinin 1 (NK1) receptor antagonist with a Ki of 0.66 nM. Rolapitant hydrochloride hydrate does not interact with CYP3A4. Rolapitant hydrochloride hydrate shows potent anti-emetic activity in a ferret emesis model[1][2].
Molecular Weight:
554.95
Purity:
98.36
CAS Number:
[914462-92-3]
Formula:
C25H29ClF6N2O3
Target:
Neurokinin Receptor
Application Notes:
MCE Product type: Reference compound
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