SST0116CL1 (free base), CAS [[1202920-93-1]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-164399A
Supplier Catalog Number:
HY-164399A
Alternative Catalog Number:
MCE-HY-164399A-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
SST0116CL1 free base is a HSP90 inhibitor (IC50: 0.21 µM). SST0116CL1 free base binds to the ATP binding pocket of Hsp90, and interferes with Hsp90 chaperone function thus resulting in client protein (EGFR, CDK4 and AKT) degradation. SST0116CL1 free base induces degradation of Her2 in BT-474 cell (IC50: 0.2 µM). SST0116CL1 free base has antiproliferative activity and inhibits tumor growth. SST0116CL1 free base has antiproliferative activity and inhibits tumor growth. SST0116CL1 free base can be used for the study of leukemia, gastric and ovarian carcinoma[1].
Molecular Weight:
446.50
CAS Number:
[1202920-93-1]
Formula:
C22H30N4O6
Target:
Akt,CDK,ERK,HSP
Application Notes:
MCE Product type: Reference compound
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