VIP236 is a small-molecule-drug conjugates (SMDCs) consisting of an alphavbeta3 integrin binder linked to an optimized Camptothecin (HY-16560) topoisomerase I (TOP1) inhibitor payload. VIP236 exerts anticancer activity by targeting alphavbeta3 integrins, and it can release payload upon cleavage by neutrophil elastase in the tumor microenvironment[1].
Molecular Weight:
1515.55
CAS Number:
[2418533-90-9]
Formula:
C72H84N12Na2O20S
Target:
Elastase,Integrin
Application Notes:
MCE Product type: Reference compound
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