A-1248767 is a MCL-1 inhibitor (IC50=23.9 nM, Ki=0.41 nM) with anticancer activity. A-1248767, a derivative of A-1210477 (HY-12468), binds to MCL-1 with high affinity, induces the increase of intracellular MCL-1 protein, and promotes tumor cell apoptosis[1].
Molecular Weight:
813.98
CAS Number:
[2228052-38-6]
Formula:
C47H55N7O6
Target:
Apoptosis,Bcl-2 Family
Application Notes:
MCE Product type: Reference compound
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