AZD1897 is a PIM1, PIM2, and PIM3 inhibitor with IC50 values of less than 3 nM for these three PIM kinases. AZD1897 exhibits anticancer activity and synergistically inhibits the activity of acute myeloid leukemia (AML) cells in combination with Capivasertib (HY-15431). This synergistic inhibitory effect is achieved through the inhibition of the mTOR and MCL1 pathways[1][2].
Molecular Weight:
361.46
Purity:
99.69
CAS Number:
[1204181-93-0]
Formula:
C18H23N3O3S
Target:
Pim
Application Notes:
MCE Product type: Reference compound
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