G-631 is an orally active tankyrase(TNKS1/TNKS2) inhibitor. G-631 stabilizes AXIN and inhibits the Wnt/beta-catenin signaling pathway. G-631 exhibits weak anti-tumor activity in mouse models of colorectal cancer. G-631 can be used in studies related to cancers such as colorectal cancer[1].
Molecular Weight:
420.41
Purity:
99.88
CAS Number:
[1507370-78-6]
Formula:
C19H22F2N6O3
Target:
PARP,Wnt,beta-catenin
Application Notes:
MCE Product type: Reference compound
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