HS-345 is a TrkA/Ak inhibitor with significant anti-pancreatic cancer effects. HS-345 inhibits the growth and proliferation of pancreatic cancer cells by targeting the TrkA/Akt signaling pathway, while also inducing apoptosis. Additionally, HS-345 suppresses blood vessel formation by decreasing the expression of HIF-1alpha and VEGF. HS-345 holds promise for research in pancreatic cancer[1].
Molecular Weight:
394.45
CAS Number:
[1462329-41-4]
Formula:
C19H18N6O2S
Target:
Akt,Trk Receptor
Application Notes:
MCE Product type: Reference compound
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