LSN3074753, CAS [[1455031-68-1]] Preis auf Anfrage

Product Overview

• Article Name: LSN3074753, CAS [[1455031-68-1]] Preis auf Anfrage
• Biozol Catalog Number: MCE-HY-164492
• Supplier Catalog Number: HY-164492
• Alternative Catalog Number: MCE-HY-164492-1UNIT
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

LSN3074753, an analog of LY3009120 (HY-12558), is a pan-RAF and Raf dimer inhibitor. LSN3074753 demonstrates activity against tumor cells with MAPK pathway activation driven by BRAF monomer or RAF dimers including BRAF- or KRAS-mutant colorectal cancer. LSN3074753 combined with Cetuximab (HY-P9905) shows additive and synergistic effects for colorectal cancer PDX models, particularly those with KRAS or BRAF mutation[1][2].

Product Properties

• Molecular Weight: 439.53
• CAS Number: [1455031-68-1]
• Formula: C24H30FN5O2
• Target: Raf

Application Notes

• Application Notes: MCE Product type: Reference compound