Sob-AM2 is a potent substrate (Km=1.3 µM) targeting fatty acid amide hydrolase (FAAH) expressed in the brain and has blood-brain barrier permeability. Sob-AM2 delivers high concentrations of Sobetirome (HY-14823) to the central nervous system with minimal peripheral systemic dose, thereby stimulating central thyroid hormone receptor beta (TRbeta). In addition, Sob-AM2 can prevent myelin and axon degeneration in experimental autoimmune encephalomyelitis (EAE) mice[1].
Molecular Weight:
341.44
Purity:
98.5
CAS Number:
[2128258-47-7]
Formula:
C21H27NO3
Target:
FAAH,Thyroid Hormone Receptor
Application Notes:
MCE Product type: Reference compound
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