NHTD is a KRAS-PDEdelta inhibitor. NHTD targets the prenyl-binding pocket of PDEdelta, altering the cellular localization of KRAS, thereby inhibiting the proliferation of KRAS-mutant cancer cells and inducing apoptosis. NHTD can be used for research on KRAS-driven non-small cell lung cancer (NSCLC)[1].
Molecular Weight:
422.47
CAS Number:
[2540915-70-4]
Formula:
C24H26N2O5
Target:
Phosphodiesterase (PDE),Ras
Application Notes:
MCE Product type: Reference compound
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