ONO-7579 is an orally active TRKA inhibitor that suppresses tumor growth by inhibiting the phosphorylation of TRKA. In colorectal cancer cells KM12, its EC50 is 17.6 ng/g (meaning that when each gram of tumor tissue contains 17.6 ng of ONO-7579, the activity of phosphorylated TRKA in the tumor is inhibited by 50%). ONO-7579 can be used in cancer research[1].
Molecular Weight:
578.95
CAS Number:
[1622212-25-2]
Formula:
C24H18ClF3N6O4S
Target:
Trk Receptor
Application Notes:
MCE Product type: Reference compound
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