PF-3837 is an Mps1 kinase inhibitor with a Ki value of 0.33 nM and an IC50 value of 5.5 nM. PF-3837 interferes with the cell cycle checkpoint by inhibiting Mps1 catalytic activity, reducing genomic stability, thereby inducing cancer cell apoptosis (Apoptosis). PF-3837 can be used in research on breast cancer[1].
Molecular Weight:
422.48
CAS Number:
[2772910-13-9]
Formula:
C21H26N8O2
Target:
Apoptosis,Mps1
Application Notes:
MCE Product type: Reference compound
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