PMED-1 is a beta-catenin inhibitor that significantly reduces beta-catenin activity in hepatoblastoma cells and various HCC cells, with an IC50 value ranging from 4.87 to 32 µM. PMED-1 affects Wnt signaling by decreasing the interaction between beta-catenin and CREB binding protein, thereby inhibiting cell proliferation. PMED-1 has potential applications in cancer research[1].
Molecular Weight:
335.37
CAS Number:
[491828-75-2]
Formula:
C20H18FN3O
Target:
Wnt
Application Notes:
MCE Product type: Reference compound
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