TMU 35435 is a histone deacetylase (HDAC) inhibitor. TMU-35435 inhibits the NHEJ pathway through ubiquitination of DNA-dependent protein kinase catalytic subunit (DNA-PKcs). In addition, TMU 35435 enhances radiosensitivity by inducing misfolded protein aggregation and autophagy in TNBC[1][2].
Molecular Weight:
379.45
CAS Number:
[2231800-32-9]
Formula:
C22H25N3O3
Target:
Autophagy,HDAC
Application Notes:
MCE Product type: Reference compound
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