XMD15-44 is a RET kinase inhibitor.XMD15-44 has a growth-inhibitory effect on RET/C634R and RET/M918T transformed RAT1 cells, with IC50 values of 11.5 nM and 8.3 nM, respectively. XMD15-44 can inhibit RET kinase and signaling in human thyroid cancer cell lines carrying oncogenic RET alleles, reducing cell proliferation[1].
Molecular Weight:
506.56
CAS Number:
[1240489-67-1]
Formula:
C29H29F3N4O
Target:
RET
Application Notes:
MCE Product type: Reference compound
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