AMD 3329 (octahydrobromide), CAS [[170861-77-5]] Preis auf Anfrage

Product Overview

• Article Name: AMD 3329 (octahydrobromide), CAS [[170861-77-5]] Preis auf Anfrage
• Biozol Catalog Number: MCE-HY-164682
• Supplier Catalog Number: HY-164682
• Alternative Catalog Number: MCE-HY-164682-1UNIT
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

AMD 3329 octahydrobromide is a potent and selective anti-HIV-1 and HIV-2 compound with activity to inhibit viral replication. AMD 3329 blocks viral invasion by binding to the chemokine receptor CXCR4. AMD 3329 exhibits EC50 values as low as 0.8 and 1.6 nM when inhibiting HIV-1 and HIV-2 replication, showing better antiviral efficacy than AMD3100. AMD 3329 significantly inhibits the binding of specific CXCR4 monoclonal antibodies and the Ca(2+) flux induced by SDF-1alpha. AMD 3329 is also able to effectively interfere with virus-induced syncytium formation, with an EC50 value of 12 nM[1].

Product Properties

• Molecular Weight: 1218.11
• CAS Number: [170861-77-5]
• Formula: C34H58Br8N8
• Target: CXCR,HIV

Application Notes

• Application Notes: MCE Product type: Reference compound1