PKCTheta-IN-2 (compound 14) is a potent and selective PKCtheta inhibitor with an IC50 of 0.25 nM. PKCTheta-IN-2 shows good selectivity over a wide range of kinases, including the PKC subfamily (30 kinases). PKCTheta-IN-2 inhibits the IL-2 production in a mouse (IC50 of 682 nM)[1].
Molecular Weight:
413.47
Purity:
99.49
CAS Number:
[1810742-60-9]
Formula:
C24H23N5O2
Target:
PKC
Application Notes:
MCE Product type: Reference compound
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