AY 25674 is an orally active antiallergic agent and a PDE inhibitor. AY 25674 inhibits the release of allergic histamine from mast cells. AY 25674 suppresses passive anaphylaxis induced by reaginic (IgE) antibodies. AY 25674 does not inhibit the increased vascular permeability caused by non-reaginic antibodies, serotonin or histamine. AY 25674 reaches its peak activity shortly after administration, rapid tolerance occurs at high doses. AY 25674 can be used in research related to passive anaphylaxis[1][2].
Molecular Weight:
221.21
CAS Number:
[65425-48-1]
Formula:
C11H11NO4
Target:
Phosphodiesterase (PDE)
Application Notes:
MCE Product type: Reference compound
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