CP-615003 is a potent and subtype-selective partial agonist of GABAA receptor (GABAA receptor) (Ki = 1.1 µM). CP-615003 is mainly converted into the active metabolite CP-900725 through oxidative deamination in monkeys and humans, and the latter also has GABAA receptor affinity. CP-615003 is a substrate of P-glycoprotein (P-gp/MDR1), resulting in severe limitation of its penetration into the central nervous system (CNS). CP-615003 can be used for the study of CNS-related indications[1].
Molecular Weight:
373.42
CAS Number:
[329016-45-7]
Formula:
C20H24FN3O3
Target:
GABA Receptor
Application Notes:
MCE Product type: Reference compound
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