Trimedoxime (TMB-4) is a blood-brain barrier-permeable cholinesterase reactivator. Trimedoxime reactivates cholinesterase inhibited by paraoxon, sarin, tabun and other agents, restricts the breakdown of acetylcholine and alleviates excessive cholinergic stimulation. Trimedoxime reduces mortality and prolongs survival time. Trimedoxime exhibits reactivation efficacy against AChE in rat tissues. Trimedoxime can be used in research related to organophosphate (paraoxon) poisoning and tabun poisoning[1][2][3].
Molecular Weight:
446.14
CAS Number:
[56-97-3]
Formula:
C15H18Br2N4O2
Target:
Cholinesterase (ChE)
Application Notes:
MCE Product type: Reference compound
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