X-376 is a potent and highly specific ALK tyrosine kinase inhibitor (TKI) (IC50=0.61 nM). X-376 is a less potent inhibitor of MET (IC50=0.69 nM). X-376 displays potent anti-tumor activity[1].
Molecular Weight:
547.41
Purity:
98.10
CAS Number:
[1365267-27-1]
Formula:
C25H25Cl2FN6O3
Target:
Anaplastic lymphoma kinase (ALK),c-Met/HGFR
Application Notes:
MCE Product type: Reference compound
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