PNU-159682, a metabolite of the anthracycline Nemorubicin, is a highly potent DNA topoisomerase II inhibitor with excellent cytotoxicity. PNU-159682 acts as a more potent and tolerated ADC cytotoxin than Doxorubicin for ADC synthesis. PNU-159682 can be used in EDV-nanocell technology to overcome agent resistance.
Molecular Weight:
641.62
Purity:
98.57
CAS Number:
[202350-68-3]
Formula:
C32H35NO13
Target:
ADC Payload,Topoisomerase
Application Notes:
MCE Product type: ADC Related
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