BRD4770 is a histone methyltransferase G9a inhibitor. BRD4770 reduces di- and trimethylation of lysine 9 on histone H3 (H3K9) with an EC50 of 5 µM, and has less or little effect toward H3K27me3, H3K36me3, H3K4me3, and H3K79me3. BRD4770 can activate the ataxia telangiectasia mutated (ATM) pathway and induce cell senescence[1].
Molecular Weight:
413.47
Purity:
99.69
CAS Number:
[1374601-40-7]
Formula:
C25H23N3O3
Target:
Histone Methyltransferase
Application Notes:
MCE Product type: Reference compound
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