Remodelin is an orally active and selective inhibitor of acetyltransferase NAT10. Remodelin inhibits NAT10 activitity and slows DNA replication and suppresses growth of prostate cancer cells. Remodelin inhibits the growth of prostate cancer and hepatocellular carcinoma in xenograft model. Remodelin enhances the healthspan in hutchinson-gilford progeria syndrome (HGPS) mouse model[1][2][3][4].
Molecular Weight:
282.36
Purity:
99.84
CAS Number:
[949912-58-7]
Formula:
C15H14N4S
Target:
Histone Acetyltransferase
Application Notes:
MCE Product type: Reference compound
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