Remodelin hydrobromide is an orally active and selective inhibitor of acetyltransferase NAT10. Remodelin hydrobromide inhibits NAT10 activitity and slows DNA replication and suppresses growth of prostate cancer cells. Remodelin hydrobromide inhibits the growth of prostate cancer and hepatocellular carcinoma in xenograft model. Remodelin hydrobromide enhances the healthspan in hutchinson-gilford progeria syndrome (HGPS) mouse model[1][2][3][4].
Molecular Weight:
363.28
Purity:
99.60
CAS Number:
[1622921-15-6]
Formula:
C15H15BrN4S
Target:
Histone Acetyltransferase
Application Notes:
MCE Product type: Reference compound
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