Dagrocorat (PF-00251802) hydrochloride is an orally active and selective high-affinity partial agonist of the glucocorticoid receptor. Dagrocorat hydrochloride is also a time-dependent reversible inhibitor of CYP3A (IC50=1.3 µM in human liver microsomes) and CYP2D6 (Ki=0.57 µM in human liver microsomes). Dagrocorat hydrochloride can be used for the research of rheumatoid arthritis[1].
Molecular Weight:
531.01
Purity:
99.85
CAS Number:
[1044535-61-6]
Formula:
C29H30ClF3N2O2
Target:
Cytochrome P450,Glucocorticoid Receptor
Application Notes:
MCE Product type: Reference compound
* VAT and and shipping costs not included. Errors and price changes excepted
