Calactin is a glycoside that can be isolated from Asclepias curassavica L.. Calactin activates caspase-3, caspase-8, caspase-9, and phosphorylates ERK. Calactin induces DNA damage, apoptosis, PARP cleavage, G2/M phase cell cycle arrest, shifts Bax/Bcl-2 expression, and shows anti-proliferation effects in leukemia cells. Calactin can be used for the research of leukemia[1].
Molecular Weight:
532.63
CAS Number:
[20304-47-6]
Formula:
C29H40O9
Target:
Apoptosis,Bcl-2 Family,Caspase,CDK,ERK,PARP
Application Notes:
MCE Product type: Reference compound
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