DDR1-IN-9 is a selective inhibitor of DDR1 with significant kinase activity suppression, exhibiting a Kd value of 4.7 nM and an IC50 value of 9.4 nM. DDR1-IN-9 demonstrates reduced potency against a diverse panel of 400 nonmutated kinases, indicating its specificity. Additionally, DDR1-IN-9 shows favorable pharmacokinetic properties and potential therapeutic effects in a model of pulmonary fibrosis.
Molecular Weight:
492.50
Purity:
99.64
CAS Number:
[1934246-20-4]
Formula:
C26H23F3N6O
Target:
Discoidin Domain Receptor
Application Notes:
MCE Product type: Reference compound
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