Grapiprant (CJ-023423) is a selective EP4 receptor antagonist whose physiological ligand is prostaglandin E2 (PGE2). Grapiprant displaces [3H]-PGE2 (1 nM) binding to dog recombinant EP4 receptor with IC50 value of 35 nM and Ki value of 24 nM. Grapiprant has the potential for osteoarthritic pain and inflammation treatment[1][2][3] .
Molecular Weight:
491.61
Purity:
99.57
CAS Number:
[415903-37-6]
Formula:
C26H29N5O3S
Target:
Prostaglandin Receptor
Application Notes:
MCE Product type: Reference compound
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