YLIU-4-105-1 is a Type II JAK2 inhibitor. YLIU-4-105-1 binds to the ATP-binding pocket of JH1. YLIU-4-105-1 has in vivo pharmacodynamic activity as evidenced by inhibiting pSTAT5, reducing spleen to body weight, and lowering blood reticulocyte counts in a dose-dependent manner[1].
Molecular Weight:
605.65
Purity:
99.39
CAS Number:
[2417685-83-5]
Formula:
C32H34F3N7O2
Target:
JAK
Application Notes:
MCE Product type: Reference compound
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