MRS4833 (compound 15) is an orally active, potent, competitive P2Y14R antagonist with an of IC50 of 5.92 nM for hP2Y14R and an IC50 of 4.8 nM for mP2Y14R. MRS4833 reduces airway eosinophilia in a protease-mediated asthma model and reverses chronic neuropathic pain in a mouse CCI model[1].
Molecular Weight:
503.51
CAS Number:
[2801627-78-9]
Formula:
C30H24F3NO3
Target:
P2Y Receptor
Application Notes:
MCE Product type: Reference compound
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