MLS-0053105, a chloromaleimide, is a selective BFL-1 inhibitor with an IC50 of 0.4 µM for Bfl-1/F-Bid. MLS-0053105 shows over 10 times less potent inhibition of Bcl-W, Bcl-2, and Bcl-XL and no activity against Bcl-B and Mcl-1[1].
Molecular Weight:
374.65
Purity:
98.89
CAS Number:
[370572-36-4]
Formula:
C15H14Cl3N3O2
Target:
Bcl-2 Family,Ligands for Target Protein for PROTAC,RAD51
Application Notes:
MCE Product type: Reference compound
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