Ono 3307 (free base), CAS [[76472-28-1]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-167924
Supplier Catalog Number:
HY-167924
Alternative Catalog Number:
MCE-HY-167924-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
Ono 3307 Free base is a novel synthetic protease inhibitor that exhibits protective effects against acute pancreatitis by preventing hyperamylasemia and pancreatic edema. Ono 3307 Free base also inhibits the redistribution of lysosomal enzymes in acinar cells and mitigates lactic dehydrogenase discharge. Ono 3307 Free base effectively reduces cathepsin B leakage from lysosomes in a dose-dependent manner. Ono 3307 Free base is able to target trypsin (Ki=48 nM), thrombin (Ki=0.18 µM), plasma kallikrein (Ki=0.29 µM), plasmin (Ki=0.31 µM), pancreatic kallikrein (Ki=3.6 µM), and chymotrypsin (Ki=47 µM).
Molecular Weight:
334.35
CAS Number:
[76472-28-1]
Formula:
C14H14N4O4S
Target:
Kallikrein,Ser/Thr Protease,Thrombin
Application Notes:
MCE Product type: Reference compound
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