MPO-IN-8 is an orally active myeloperoxidase (MPO) inhibitor. MPO-IN-8 can inhibit the generation of hypochlorous acid in neutrophils and the release of extracellular traps (NETosis). In mice with gouty arthritis, MPO-IN-8 can reduce swelling, lower peroxidase activity, and decrease IL-1beta levels[1].
Molecular Weight:
227.22
CAS Number:
[62578-87-4]
Formula:
C12H9N3O2
Target:
Others
Application Notes:
Reference compound
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