GPX4-IN-14 (compound 2c) is an inhibitor of GPX4, with free radical scavenging activity (maximum scavenging rate is 72.52%) and anti-tumor proliferation activity in vitro. GPX4-IN-14 inhibits GPX4 protein, increases lipid peroxide levels and intracellular Reactive Oxygen Species (ROS) levels, thereby inducing ferroptosis and exerting anti-tumor proliferation effects[1].
Molecular Weight:
572.55
Formula:
C26H39NO8Se
Target:
Ferroptosis,Glutathione Peroxidase,Reactive Oxygen Species (ROS)
Application Notes:
Reference compound
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