KRASG12C IN-14 (compound 15) is an inhibitor targeting the KRAS G12C mutation. KRASG12C IN-14 inhibits CYPA-dependent KRAS-BRAF with an IC50 of 0.002 µM. KRASG12C IN-14 inhibits ERK phosphorylation in NCI-H358 cells with an IC50 of 0.002 µM[1].
Molecular Weight:
1088.24
Formula:
C51H65F4N9O9S2
Target:
Ras
Application Notes:
Reference compound
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