Dot1L-IN-8 (Compound 15) is a potent Dot1L inhibitor. Dot1L-IN-8 inhibits HL-60, K562, MV4-11, HH, and KG-1 cells vitality with IC50s of 0.45, 1.03, 0.68, 1.66, and 1.12 µM, respectively[1].
Molecular Weight:
723.97
Formula:
C41H53N7O3S
Target:
Histone Methyltransferase
Application Notes:
MCE Product type: Reference compound1
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