Antiproliferative agent-60 (compound 8c) is a 11-Azaartemisinin derivative with superior anticancer activities. Antiproliferative agent-60 shows IC50 values of 7.7 µM, 42.5 µM, and 15.5 µM for epidermoid carcinoma (KB), HepG2, and A549 cells, respectively. Antiproliferative agent-60 exhibits significant tumor selectivity, up to 32-fold higher compared to Hek293 normal cells[1].
Molecular Weight:
517.42
Formula:
C24H29BrN4O4
Target:
Drug Derivative
Application Notes:
MCE Product type: Reference compound
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