PROTAC c-Met degrader-1, CAS [[3056647-52-7]] Preis auf Anfrage

Product Overview

• Article Name: PROTAC c-Met degrader-1, CAS [[3056647-52-7]] Preis auf Anfrage
• Biozol Catalog Number: MCE-HY-168135
• Supplier Catalog Number: HY-168135
• Alternative Catalog Number: MCE-HY-168135-5MG,MCE-HY-168135-100MG,MCE-HY-168135-25MG,MCE-HY-168135-10MG,MCE-HY-168135-50MG
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

PROTAC c-Met degrader-1 (Compound Met-DD4) is an orally active PROTAC degrader for c-Met with a DC50 of 6.21 nM. PROTAC c-Met degrader-1 inhibits the proliferation of c-Met-addicted cell MKN-45 with an IC50 of 4.37 nM, and arrests the cell cycle at G0/G1 phase. PROTAC c-Met degrader-1 exhibits antitumor efficacy in MKN-45 xenograft mouse models[1]. (Pink: Ligand for target protein (HY-13404), Blue: Ligand for E3 ligase (HY-W087383), Black: Linker (HY-W074901))

Product Properties

• Molecular Weight: 820.87
• Purity: 98.48
• CAS Number: [3056647-52-7]
• Formula: C45H41FN10O5
• Target: c-Met/HGFR,PROTACs

Application Notes

• Application Notes: MCE Product type: Reference compound