TLR7 agonist 27 (compound 24) is a potent TLR7 agonist with an EC50 of 238.1 nM. TLR7 agonist 27 shows weak agonistic activity against NOD2 (nucleotide-binding oligomerization domain 2) (EC50 of 6.2 µM). TLR7 agonist 27 is a potent immunostimulant, and can be used as a vaccine adjuvant and/or immunotherapeutic[1].
Molecular Weight:
945.07
Formula:
C47H64N10O11
Target:
NOD-like Receptor (NLR),Toll-like Receptor (TLR)
Application Notes:
MCE Product type: Reference compound1
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