ERK1/2 inhibitor 11 (compound L6) is a dual inhibitor of ERK1/2, lending to DSB accumulation and ERK1/2 expression degradation. ERK1/2 inhibitor 11 lowers the levels of BCL-2, and induces DNA damage by inhibiting PARP and ERK1/2. ERK1/2 inhibitor 11 activates caspase 3 to inducing apoptosis.[1].
Molecular Weight:
318.39
Formula:
C15H18N4O2S
Target:
Apoptosis,Caspase,ERK
Application Notes:
MCE Product type: Reference compound
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