HSP90-IN-33 (compound 24e) is a potent Hsp90 inhibitor with Kd values of 200, 7.3 µM for Hsp90alpha, Hsp90beta, respectively. HSP90-IN-33 induces apoptosis and cell cycle arrest at G0/G1 phase. HSP90-IN-33 decreases the protein expression of ERalpha, CDK4 and Akt[1].
Molecular Weight:
450.36
Formula:
C21H25Cl2N5O2
Target:
Apoptosis,HSP
Application Notes:
MCE Product type: Reference compound
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