LBM22 is a CDC2-like kinase 2 (CLK2) inhibitor with the IC50 of 3.9 nM. LBM22 has antiproliferative activity and inhibits serine/arginine-rich (SR) protein phosphorylation. LBM22 down-regulates the expression of Wnt-related proteins and anti-apoptotic proteins and can be used for study of non-small cell lung cancer[1].
Molecular Weight:
512.51
Formula:
C28H22F2N6O2
Target:
Apoptosis,CDK,Wnt
Application Notes:
MCE Product type: Reference compound
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