NMDAR antagonist 2 (compound 3I) is a CNS penetrant NMDAR antagonist with the IC50 of 4.42 µM and 214.75 µM for hGluN1/hGluN2A at -60 mV or 40 mV membrane potentials, respectively. NMDAR antagonist 2 can reduce hippocampal damage[1].
Molecular Weight:
289.80
Formula:
C17H20ClNO
Target:
iGluR
Application Notes:
MCE Product type: Reference compound
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