PROTAC BRM/BRG1 degrader-4 (example 047) is a potent BRM and BRG1 PROTAC degrader, with DC50 values of 0.21 nM and 3.4 nM in SW1573 cells, respectively (Pink: ligand for target protein (HY-168252), Black: linker (HY-28911), Blue: E3 ligase ligand (HY-168253))[1].
Molecular Weight:
849.01
Formula:
C44H52N10O6S
Target:
Epigenetic Reader Domain,PROTACs
Application Notes:
MCE Product type: Reference compound
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