CQ-Mito is a Coumarin-Quinazolinone (CQ)-based derivative that targets mitochondria and exhibits profound phototherapeutic performances with an Phototoxic Index (PI) value of 167. CQ-Mito causes cell death by both apoptosis and ferroptosis. CQ-Mito mediates mitochondrial dysfunction, including mitochondrial morphology changed and the loss of MMP. CQ-Mito can efficiently inhibit the tumor growth in organoid tumor models[1].
Molecular Weight:
841.73
Formula:
C45H42BrN6O4P
Target:
Apoptosis,Ferroptosis,MMP
Application Notes:
MCE Product type: Reference compound
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