Tyk2-IN-22 (Compound A8) is a selective inhibitor for tyrosine kinase 2 (Tyk2), that it inhibits Tyk2, JAK1, and JAK3 with IC50s of 9.7, 148.6, and 883.3 nM, respectively. Tyk2-IN-22 inhibits the downstream STAT5 phosphorylation[1].
Molecular Weight:
345.78
CAS Number:
[933667-23-3]
Formula:
C16H16ClN5O2
Target:
JAK
Application Notes:
MCE Product type: Reference compound
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