Keap1-Nrf2-IN-24 (compound 57) is a potent Keap1-Nrf2 inhibitor with a Ki value of 13 nM. Keap1-Nrf2-IN-24 increases the protein expression of TRXR1 and NQO1. Keap1-Nrf2-IN-24 increases the AKR1B10 mRNA expression. Keap1-Nrf2-IN-24 shows good metabolic stability[1].
Molecular Weight:
596.63
Formula:
C32H25FN4O5S
Target:
Keap1-Nrf2
Application Notes:
MCE Product type: Reference compound1
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