ZG-2305 is a potent, orally active and selective factor inhibiting hypoxia-inducible factor (FIH) inhibitor with Ki values of 79.6, 2786 nM for FIH, PHD2, respectively. ZG-2305 increases the expression of EGLN3 gene. ZG-2305 decreases the cellular triglycerides levels and reduces lipid accumulation. ZG-2305 has the potential for the research of obesity and fatty liver disease[1].
Molecular Weight:
408.19
CAS Number:
[2962103-54-2]
Formula:
C17H11Cl2N3O5
Target:
HIF/HIF Prolyl-Hydroxylase
Application Notes:
MCE Product type: Reference compound
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